Links between autism and allergy

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Links between autism and allergy

Methods 251 individuals participated in this study: 1. 42 with autism without allergies 2. 42 women (mothers of the autistic patients) without autism 3. 104 allergic patients without autism 4. 63 normal health controls The ASST was performed injecting intradermically 0,05 ml of the each own serum in the volar surface of the forearm. Saline was used as a negative control. After 15 minutes the we...

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Neuroligins provide molecular links between syndromic and nonsyndromic autism.

Autism is a common and heritable neuropsychiatric disorder that can be categorized into two types: syndromic and nonsyndromic, the former of which are associated with other neurological disorders or syndromes. Molecular and functional links between syndromic and nonsyndromic autism genes were lacking until studies aimed at understanding the role of trans-synaptic adhesion molecule neuroligin, w...

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Atopic diseases are frequently co-morbid with autism spectrum disorders (ASD). Allergic responses are associated with an activation of mast cells, innate lymphoid cells, and Th2 cells. These cells produce type-2 cytokines (IL4 and IL13), which stimulate microglia and macrophages to adopt a phenotype referred to as 'alternative activation' or 'M2A'. M2A-polarized macrophages and microglia play a...

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ژورنال

عنوان ژورنال: World Allergy Organization Journal

سال: 2015

ISSN: 1939-4551

DOI: 10.1186/1939-4551-8-s1-a17